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Glycogen PRKAG2

Glycogen storage disease – Adult PRKAG2
A. Basophilic intracytoplasmic inclusions (indicated by arrows)  are seen in a number of myocytes.  Other myocytes appear pale with eosinophilic granular material in the cytoplasm. H&E.  B.  The inclusions are stained with periodic acid Schiff and are resistant to digestion with diastase indicative of abnormal glycogen accumulation.

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